CP-506 mesylate

Chemical Structure : CP-506 mesylate

CAS No.: 2227304-19-8

加入收藏

货号: PC-25508Not For Human Use, Lab Use Only.

CP-506 mesylate is a DNA alkylating hypoxia-activated prodrug (HAP), shows selective antitumor effects for hypoxic tumor cells and causally related to tumor oxygenation.

规格	价格	库存
2 mg	￥2780	In stock
5 mg	￥4580	In stock
10 mg		Get quote
50 mg		Get quote
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

CP-506 mesylate is a DNA alkylating hypoxia-activated prodrug (HAP), shows selective antitumor effects for hypoxic tumor cells and causally related to tumor oxygenation.
CP-506 is designed to be resistant to AKR1C3 metabolism, ensuring highly specific hypoxia-dependent activation.
CP-506 demonstrates cytotoxicity selectively in hypoxic 2D and 3D cell cultures with normoxic/anoxic IC50 ratios up to 203.
CP-506 effectively decreased the hypoxic fraction and inhibited growth of a wide range of hypoxic xenografts.

物理化学性质&存储条件

分子量	681.59
分子式	C20H33BrN4O11S3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-((2-bromoethyl)(5-(4-ethylpiperazine-1-carbonyl)-2-(methylsulfonyl)-4-nitrophenyl)amino)ethyl methanesulfonate mesylate

参考文献

1. van der Wiel AMA, et al. Mol Cancer Ther. 2021 Dec;20(12):2372-2383.

CP-506 mesylate

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

CP-506 mesylate

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.