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首页-小分子抑制剂&激动剂-Others-Other Targets-CN045
CN045

Chemical Structure : CN045

CAS No.: 401809-27-6

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CN045 (CN-045)

货号: PC-27367Not For Human Use, Lab Use Only.

CN045 is a brain-penetrable enhancer of oligodendrocyte progenitor cells (OPCs) differentiation and remyelination, stimulates differentiation of mouse OPCs into oligodendrocytes with EC50 of 40  nM in the OPC differentiation assay.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

CN045 is a brain-penetrable enhancer of oligodendrocyte progenitor cells (OPCs) differentiation and remyelination, stimulates differentiation of mouse OPCs into oligodendrocytes with EC50 of 40  nM in the OPC differentiation assay.
CN045 promotes myelin-like ensheathment of engineered nanofibers.
CN045 increases human OPC differentiation and ensheathment of nanofibers.
CN045 enhances remyelination in the Cuprizone/Rapamycin demyelinating mouse model.

物理化学性质&存储条件

分子量 366.71
分子式 C16H22Cl3NO2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4-methyl-1-(2-(2-(2,4,6-trichlorophenoxy)ethoxy)ethyl)piperidine

参考文献

1. Yang Y, et al. NPJ Drug Discov. 2026 Jul 23;3(1):24.

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