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首页-小分子抑制剂&激动剂-Immunology/Inflammation-Toll-like Receptor (TLR)-CL097
CL097

Chemical Structure : CL097

CAS No.: 1026249-18-2

CL097 (CL-097)

货号: PC-25432Not For Human Use, Lab Use Only.

CL097 is a specific small molecule TLR-7/TLR-8 agonist, inhibits TLR-4--dependent activation of IRAK-M and BCL-3 expression, induces human pDC activation.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

CL097 is a specific small molecule TLR-7/TLR-8 agonist, inhibits TLR-4 dependent activation of IRAK-M and BCL-3 expression, induces human pDC activation.

物理化学性质&存储条件

分子量 242.28
分子式 C13H14N4O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(Ethoxymethyl)-3H-imidazo[4,5-c]quinolin-4-amine

参考文献

1. Petricevic B, et al. Shock. 2009 Nov;32(5):484-90.

2. Di Domizio J, et al. Blood. 2009 Aug 27;114(9):1794-802.

3. Eissmann P, et al. J Immunol. 2010 Jun 15;184(12):6901-9.

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