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首页-新冠病毒相关-SARS-CoV-2 Inhibitors-CKP-25
CKP-25

Chemical Structure : CKP-25

CAS No.: 3126210-69-0

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CKP-25

货号: PC-28706Not For Human Use, Lab Use Only.

CKP-25 is a small molecule severe-acute-respiratory syndrome coronavirus 2 (SARS-CoV-2) inhibitor, suppresses the Spike RBD/ACE2 (19-615) interaction, reduces the cytopathic effect of SARS-CoV-2 in Vero E6 cells with IC50 of 3.5 uM, reduces the viral load in cell culture supernatants.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

CKP-25 is a small molecule severe-acute-respiratory syndrome coronavirus 2 (SARS-CoV-2) inhibitor, suppresses the Spike RBD/ACE2 (19-615) interaction, reduces the cytopathic effect of SARS-CoV-2 in Vero E6 cells with IC50 of 3.5 uM, reduces the viral load in cell culture supernatants.

物理化学性质&存储条件

分子量 288.35
分子式 C19H16N2O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4-methoxy-1-(naphthalen-2-ylmethyl)-1H-benzo[d]imidazole

参考文献

1. Gkekas I, et al. J Chem Inf Model. 2024 Nov 25;64(22):8562-8585.

2. Papadopoulos AM, et al. Pharmaceuticals (Basel). 2026 Oct 21;19(10):1664.

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