欢迎访问ProbeChem中文网站,英文网站请访问www.probechem.com

首页-小分子抑制剂&激动剂-Wnt/Notch/Hedgehog-Casein Kinase-CK2 inhibitor TF
CK2 inhibitor TF

Chemical Structure : CK2 inhibitor TF

CAS No.: 84989-95-7

CK2 inhibitor TF

货号: PC-26375Not For Human Use, Lab Use Only.

CK2 inhibitor TF is a potent, selective competitive inhibitor of protein kinase CK2 (Casein kinase 2) with Ki of 15 nM and IC50 of 29 nM.

规格 价格 库存 数量
50 mg Get quote
100 mg Get quote
250 mg Get quote

大包装,大折扣!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

CK2 inhibitor TF is a potent, selective competitive inhibitor of protein kinase CK2 (Casein kinase 2) with Ki of 15 nM and IC50 of 29 nM.
CK2 inhibitor TF addresses the nucleotide binding site of the catalytic α-subunit of CK2 and thus competes with the binding of the co-substrate ATP.
CK2 inhibitor TF does not interfere with the expression of CK2.
CK2 inhibitor TF significantly decreases cell viability and cell proliferation in prostate cancer cells.

物理化学性质&存储条件

分子量 388.24
分子式 C20H15Cl2NO3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(Z)-6,7-dichloro-8-hydroxy-4-((p-tolylamino)methylene)-1,4-dihydrodibenzo[b,d]furan-3(2H)-one

参考文献

1. Claudia Götz, et al. Biochim Biophys Acta. 2012 Jul;1820(7):970-7.

2. Anne S Boewe, et al. Molecules. 2026 Mar 9;31(5):907.

备案号:沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

联系我们 sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

询单

  • *产品名称:
  • *姓名:
  • *邮箱:
  • *公司名称:
  • *询单数量:
  • *国籍:
  • 询单信息: