Chemical Structure : CK2 inhibitor TBB
CAS No.: 17374-26-4
货号: PC-25510Not For Human Use, Lab Use Only.
TBB (4,5,6,7-tetrabromobenzotriazole) is a potent, cell-permeable and ATP-competitive CK2 inhibitor with IC50 of 0.15 uM and 1.6 uM for rat liver CK2 and human CK2 respectively.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 mg | ¥580 | In stock | |
| 50 mg | ¥880 | In stock | |
| 100 mg | ¥1280 | In stock | |
| 250 mg | Get quote |
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TBB (4,5,6,7-tetrabromobenzotriazole) is a potent, cell-permeable and ATP-competitive CK2 inhibitor with IC50 of 0.15 uM and 1.6 uM for rat liver CK2 and human CK2 respectively.
TBB also inhibits MESH1 (Metazoan SpoT Homologue 1) with an IC50 value of 4.7 uM.
| 分子量 | 434.71 | |
| 分子式 | C6HBr4N3 | |
| 外观性状 | Solid | |
| 储存条件 |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
4,5,6,7-tetrabromobenzotriazole |
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1. Sarno S, et al. FEBS Lett. 2001 May 4;496(1):44-8.
2. De Moliner E, et al. Eur J Biochem. 2003 Aug;270(15):3174-81.
3. Orzechowska E, et al. Oncol Rep. 2012 Jan;27(1):281-5.
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