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首页-小分子抑制剂&激动剂-Wnt/Notch/Hedgehog-Casein Kinase-CK2 inhibitor TBB
CK2 inhibitor TBB

Chemical Structure : CK2 inhibitor TBB

CAS No.: 17374-26-4

CK2 inhibitor TBB (4,5,6,7-tetrabromobenzotriazole)

货号: PC-25510Not For Human Use, Lab Use Only.

TBB (4,5,6,7-tetrabromobenzotriazole) is a potent, cell-permeable and ATP-competitive CK2 inhibitor with IC50 of 0.15 uM and 1.6 uM for rat liver CK2 and human CK2 respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

TBB (4,5,6,7-tetrabromobenzotriazole) is a potent, cell-permeable and ATP-competitive CK2 inhibitor with IC50 of 0.15 uM and 1.6 uM for rat liver CK2 and human CK2 respectively.
TBB also inhibits MESH1 (Metazoan SpoT Homologue 1) with an IC50 value of 4.7 uM.

物理化学性质&存储条件

分子量 434.71
分子式 C6HBr4N3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4,5,6,7-tetrabromobenzotriazole

参考文献

1. Sarno S, et al. FEBS Lett. 2001 May 4;496(1):44-8.

2. De Moliner E, et al. Eur J Biochem. 2003 Aug;270(15):3174-81.

3. Orzechowska E, et al. Oncol Rep. 2012 Jan;27(1):281-5.

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