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首页-小分子抑制剂&激动剂-Wnt/Notch/Hedgehog-Casein Kinase-CK2A2 inhibitor 65
CK2A2 inhibitor 65

Chemical Structure : CK2A2 inhibitor 65

CAS No.:

CK2A2 inhibitor 65

货号: PC-24634Not For Human Use, Lab Use Only.

CK2A2 inhibitor 65 is a selective, brain-penetrant inhibitor of CK2A2 and CK2A2 with IC50 of 3 nM and 4 nM respectively.

规格 价格 库存 数量
25 mg Get quote
50 mg Get quote
100 mg Get quote

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

CK2A2 inhibitor 65 is a selective, brain-penetrant inhibitor of CK2A2 and CK2A2 with IC50 of 3 nM and 4 nM respectively.
CK2A2 inhibitor 65 shares dual-specificity tyrosine phosphorylation-regulated kinase 2 (DYRK2) as a kinome off-target with SGC-CK2-1 and CX-4945.

物理化学性质&存储条件

分子量 373.16
分子式 C16H9BrN2O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

8-bromo-2-(5-hydroxy-6-methoxypyridin-2-yl)-4-oxo-4H-chromene-6-carbonitrile

参考文献

1. James K Tucker, et al. Bioorg Med Chem. 2025 Apr 16:127:118196.

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