CK1γ inhibitor 1h

Chemical Structure : CK1γ inhibitor 1h

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货号: PC-25590Not For Human Use, Lab Use Only.

CK1γ inhibitor 1h is a potent, selective inhibitor of casein kinase 1γ (CK1γ) with IC50 of 18 nM, has >100-fold selective over CK1α, CK1δ and GSK3β, inhibits phosphorylation of LRP6 in HEK293 cell with IC50 of 0.7 uM.

规格	价格	库存	数量
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

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生物&药学活性

物理化学性质&存储条件

分子量	292.34
分子式	C17H16N4O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-((4-(2-hydroxypropan-2-yl)phenyl)amino)-1H-benzo[d]imidazole-6-carbonitrile

参考文献

1. Hua Z, et al. Bioorg Med Chem Lett. 2012 Sep 1;22(17):5392-5.

2. Capener JL, et al. bioRxiv [Preprint]. 2025 Sep 16:2025.09.10.675406.