CHI3L1 inhibitor G28

Chemical Structure : CHI3L1 inhibitor G28

CAS No.: 1207253-08-4

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货号: PC-24717Not For Human Use, Lab Use Only.

CHI3L1 inhibitor G28 is a potent small molecule CHI3L1 binder/inhibitor with KD of 51.4 uM.

规格	价格	库存
5 mg	￥1580	In stock
10 mg	￥2480	In stock
25 mg	￥4280	In stock
100 mg		Get quote

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生物&药学活性

CHI3L1 inhibitor G28 is a potent small molecule CHI3L1 binder/inhibitor with KD of 51.4 uM.
G28 significantly outperformed reported CHI3L1 small molecule modulators, showing the most pronounced dose-dependent reductions in spheroid weight, migration, and viability in 3D GBM spheroid models.

物理化学性质&存储条件

分子量	461.91
分子式	C24H20ClN5O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	[2,2':5',3''-Terpyridine]-3'-carboxamide, 5''-chloro-N-[(5,6-dimethoxy-2-pyridinyl)methyl]-

参考文献

1. Hossam Nada, et al. bioRxiv [Preprint]. 2025 May 17:2025.05.13.653859.