CHI3L1 inhibitor 9e

Chemical Structure : CHI3L1 inhibitor 9e

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货号: PC-25373Not For Human Use, Lab Use Only.

CHI3L1 inhibitor 9e is a small molecule inhibitor of Chitinase 3-like 1 (CHI3L1) with SPR KD of 19.11 uM, inhibits CHI3L1-STAT3 axis and elicits a dose-dependent reduction in pSTAT3 in GBM spheroids.

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250 mg		Get quote

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生物&药学活性

CHI3L1 inhibitor 9e is a small molecule inhibitor of Chitinase 3-like 1 (CHI3L1) with SPR KD of 19.11 uM, inhibits CHI3L1-STAT3 axis and elicits a dose-dependent reduction in pSTAT3 in GBM spheroids.

物理化学性质&存储条件

分子量	277.75
分子式	C14H16ClN3O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5-chloro-N-(2-(5-methyl-1,2,4-oxadiazol-3-yl)ethyl)-2,3-dihydro-1H-inden-2-amine

参考文献

1. Kaur B, et al. bioRxiv [Preprint]. 2025 Aug 12:2025.08.09.669500.