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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Chitinase-CHI3L1 inhibitor 1-7
CHI3L1 inhibitor 1-7

Chemical Structure : CHI3L1 inhibitor 1-7

CAS No.: 2248987-74-6

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CHI3L1 inhibitor 1-7

货号: PC-25397Not For Human Use, Lab Use Only.

CHI3L1 inhibitor 1-7 is potent CHI3L1 binder with KD of 7.4 uM, inhibits the interaction between CHI3L1 and galectin-3 with IC50 of 15.4 uM, reduces GBM spheroid viability and inhibits STAT3 activation.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

CHI3L1 inhibitor 1-7 is potent CHI3L1 binder with KD of 7.4 uM, inhibits the interaction between CHI3L1 and galectin-3 with IC50 of 15.4 uM, reduces GBM spheroid viability and inhibits STAT3 activation.

物理化学性质&存储条件

分子量 357.43
分子式 C17H19N5O2S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-(1-cyclopentyl-5-methyl-1H-pyrazol-4-yl)-2-(4-oxothieno[2,3-d]pyrimidin-3(4H)-yl)acetamide

参考文献

1. Longfei Zhang, et al. bioRxiv [Preprint]. 2025 Aug 27:2025.08.24.671973.

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