CHF-6333 | Neutrophil elastase inhibitor | Probechem Biochemicals

Chemical Structure : CHF-6333

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货号: PC-25805Not For Human Use, Lab Use Only.

CHF-6333 is is a potent, selective neutrophil elastase (NE) inhibitor with IC50 of 0.22 nM for human neutrophil elastase (HNE).

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CHF-6333 is is a potent, selective neutrophil elastase (NE) inhibitor with IC50 of 0.22 nM for human neutrophil elastase (HNE).

分子量	621.46
分子式	C27H28BrF3N6O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2-{5-Cyano-2-[(R)-6-methoxycarbonyl-7-methyl-3-oxo-8-(3-trifluoromethyl-phenyl)-2,3,5,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrimidin-5-yl]-phenyl}-ethyl)-trimethylammonium bromide

1. Armani E, et al. J Med Chem. 2025 Nov 27. doi: 10.1021/acs.jmedchem.5c02638.