CGRP receptor antagonist 15

Chemical Structure : CGRP receptor antagonist 15

加入收藏

货号: PC-24985Not For Human Use, Lab Use Only.

CGRP receptor antagonist 15 is a highly potent, orally bioavailable calcitonin gene-related peptide (CGRP) receptor antagonist with Ki of 0.029 nM and cAMP IC50 of 0.17 nM.

规格	价格	库存	数量
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

CGRP receptor antagonist 15 is a highly potent, orally bioavailable calcitonin gene-related peptide (CGRP) receptor antagonist with Ki of 0.029 nM and cAMP IC50 of 0.17 nM.

物理化学性质&存储条件

分子量	529.62
分子式	C30H32FN5O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(2-((2R,5S)-2-(2-Cyanopropan-2-yl)-5-(3-fluorophenyl)pyrrolidin-1-yl)-2-oxoethyl)-3-methyl-4-((6-methyl-3-oxo-2,3-dihydropyridazin-4-yl)methyl)benzamide

参考文献

1. Morita N, et al. J Med Chem. 2025 Jul 3. doi: 10.1021/acs.jmedchem.5c01127.