CG3-46

Chemical Structure : CG3-46

加入收藏

货号: PC-24531Not For Human Use, Lab Use Only.

CG3-46 is a specific nonpeptide small molecule CBX2 inhibitor, inhibits the interaction between CBX2 and H3K27me3 with IC50 of 15.4 μM and 14.6 μM in NanoBRET and NanoBiT assays, respectively.

规格	价格	库存	数量
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

CG3-46 is a specific nonpeptide small molecule CBX2 inhibitor, inhibits the interaction between CBX2 and H3K27me3 with IC50 of 15.4 μM and 14.6 μM in NanoBRET and NanoBiT assays, respectively.
CG3-46 inhibits the CBX2-H3K27me3 interaction without affecting H3K27me3 in cells.
CG3-46 inhibited the growth of MDA-MB-231 cells (IC50=3.3 uM) by suppressing cellular CBX2 activity.

物理化学性质&存储条件

分子量	489.33
分子式	C21H24BrF3N2O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(2-bromo-4-((butylamino)methyl)-6-methoxyphenoxy)-N-(3-(trifluoromethyl)phenyl)acetamide

参考文献

1. Takase S, et al. Biochem Biophys Res Commun. 2025 Apr 23;767:151882.

CG3-46

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

CG3-46

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.