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首页-小分子抑制剂&激动剂-Others-Other Targets-CDD-3290
CDD-3290

Chemical Structure : CDD-3290

CAS No.:

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CDD-3290 (CDD3290)

货号: PC-23067Not For Human Use, Lab Use Only.

CDD-3290 (CDD3290) is a specific small molecule inhibitor of prostate-specific antigen (PSA; KLK3) with Ki of 216 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    CDD-3290 (CDD3290) is a specific small molecule inhibitor of prostate-specific antigen (PSA; KLK3) with Ki of 216 nM.
    CDD-3290 shows minimal inhibitory activity against elastase (Ki = 1.18 mM) and is 12.7-fold less potent against α-chymotrypsin (Ki = 2.74 μM).
    CDD-3290l exhibits similar inhibition against thrombin (Ki = 0.411 μM).

    物理化学性质&存储条件

    分子量 334.34
    分子式 C17H14N6O2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (5-amino-3-(6-methoxypyridin-3-yl)-1H-pyrazol-1-yl)(1H-benzo[d]imidazol-5-yl)methanone

    参考文献

    1. Erickson JA, et al. ACS Med Chem Lett. 2024 Aug 5;15(9):1526-1532.

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