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CD73 inhibitor Compound 73

Chemical Structure : CD73 inhibitor Compound 73

CAS No.: 2412019-99-7

CD73 inhibitor Compound 73 (CD73-IN-5 )

货号: PC-27237Not For Human Use, Lab Use Only.

CD73 inhibitor Compound 73 (CD73-IN-5) is a potent and selective non-nucleotide small molecule inhibitor of CD73 (ecto-5′-nucleotidase, eN) with IC50 of 12 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    CD73 inhibitor Compound 73 (CD73-IN-5) is a potent and selective non-nucleotide small molecule inhibitor of CD73 (ecto-5′-nucleotidase, eN) with IC50 of 12 nM.

    物理化学性质&存储条件

    分子量 434.44
    分子式 C24H15FN8
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    4-((5-(4-chloro-1-(2H-indazol-6-yl)-1H-benzo[d][1,2,3]triazol-6-yl)-1H-pyrazol-1-yl)methyl)benzonitrile

    参考文献

    1. Joel W Beatty, et al. J Med Chem. 2020 Apr 23;63(8):3935-3955.

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