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CD39 inhibitor Compound 338

Chemical Structure : CD39 inhibitor Compound 338

CAS No.:

CD39 inhibitor Compound 338

货号: PC-24758Not For Human Use, Lab Use Only.

CD39 inhibitor compound 338 is a potent, selective nucleotidase NTPDase1 (CD39) inhibitor with IC50 of 68.7 nM, weakly inhibits NTPDase 2 and NTPDase 3, with IC50 values of 975.9 nM and 715.9 nM, respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

CD39 inhibitor compound 338 is a potent, selective nucleotidase NTPDase1 (CD39) inhibitor with IC50 of 68.7 nM, weakly inhibits NTPDase 2 and NTPDase 3, with IC50 values of 975.9 nM and 715.9 nM, respectively.

物理化学性质&存储条件

分子量 494.53
分子式 C29H23FN4O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(4-fluoro-3-(methylcarbamoyl)-2-(6-phenoxypyridin-3-yl)phenyl)-1-methyl-1H-indole-2-carboxamide

参考文献

1. Simin Wang, et al. Bioorg Med Chem Lett. 2025 Jun 2:130294.

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