CBR-470-2

Chemical Structure : CBR-470-2

CAS No.: 2416095-00-4

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货号: PC-24726Not For Human Use, Lab Use Only.

CBR-470-2 is a small molecule inhibitor of glycolytic enzyme phosphoglycerate kinase 1 (PGK1), activates NRF2 signaling in vitro and in vivo.

规格	价格	库存
2 mg	￥1980	In stock
5 mg	￥3480	In stock
10 mg	￥5480	In stock
25 mg		Get quote
100 mg		Get quote

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生物&药学活性

CBR-470-2 is a small molecule inhibitor of glycolytic enzyme phosphoglycerate kinase 1 (PGK1), activates NRF2 signaling in vitro and in vivo.
CBR-470-2 attenuated NF-κB signaling, decreasing transcriptional output in response to several canonical NF-κB activating stimuli.

物理化学性质&存储条件

分子量	402.26
分子式	C12H13Cl2NO6S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Glycine, N-[(3R,4S)-4-[(3,4-dichlorophenyl)sulfonyl]tetrahydro-1,1-dioxido-3-thienyl]-, rel-

参考文献

1. Bollong MJ, et, al. Nature. 2018 Oct;562(7728):600-604.

2. Caroline Stanton, et al. bioRxiv [Preprint]. 2025 May 16:2025.05.13.653579.

CBR-470-2

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CBR-470-2

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