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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Carbonic Anhydrase-CAIX inhibitor S4
CAIX inhibitor S4

Chemical Structure : CAIX inhibitor S4

CAS No.: 1330061-67-0

CAIX inhibitor S4 (CA9 inhibitor S4)

货号: PC-26516Not For Human Use, Lab Use Only.

CAIX inhibitor S4 is a potent, specific CA IX/XII inhibitor with Ki of 7 nM and 2 nM for human CA IX (CA9) and CA XII (CA12) respectively, much weakly inhibits CA II and CA I, inhibits lung metastasis in orthotopic MDA-MB-231 mouse model.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

CAIX inhibitor S4 is a potent, specific CA IX/XII inhibitor with Ki of 7 nM and 2 nM for human CA IX (CA9) and CA XII (CA12) respectively, much weakly inhibits CA II and CA I, inhibits lung metastasis in orthotopic MDA-MB-231 mouse model.

物理化学性质&存储条件

分子量 335.38
分子式 C15H17N3O4S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-(3-(3,5-Dimethylphenyl)ureido)phenyl sulfamate

参考文献

1. Gieling RG, et, al. J Med Chem. 2012 Jun 14;55(11):5591-600.

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