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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Phospholipase-Bromoenol Lactone
Bromoenol Lactone

Chemical Structure : Bromoenol Lactone

CAS No.: 88070-98-8

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Bromoenol Lactone (HELSS)

货号: PC-26700Not For Human Use, Lab Use Only.

Bromoenol Lactone (HELSS) is a potent, irreversible, selective inhibitor of calcium-independent phospholipase A2 (iPLA2, GVIA iPLA 2, iPLA2β) inhibitor with IC50 of 1 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Bromoenol Lactone (HELSS) is a potent, irreversible, selective inhibitor of calcium-independent phospholipase A2 (iPLA2, GVIA iPLA 2, iPLA2β) inhibitor with IC50 of 1 uM.

物理化学性质&存储条件

分子量 317.18
分子式 C16H13BrO2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(E)-6-(Bromomethylene)-3-(naphthalen-1-yl)tetrahydro-2H-pyran-2-one

参考文献

1. Chakraborty S, et al. J Pharmacol Exp Ther. 2011 Nov;339(2):329-40.

2. Fensome-Green A, et al. Cell Calcium. 2007 Feb;41(2):145-53.

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