Brodalumab |CAS:1174395-19-7 Probechem Biochemicals

Chemical Structure : Brodalumab

CAS No.: 1174395-19-7

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Brodalumab (Anti-human IL-17 mAb, human IgG2-Kappa; AMG-827; KHK-4827)

货号: PC-Ab1079Not For Human Use, Lab Use Only.

Brodalumab (AMG-827, KHK-4827) is a human monoclonal IgG2 antibody that selectively binds to human IL-17RA and inhibits its interactions with cytokines IL-17A, IL-17F, IL-17C, IL-17A/F heterodimer and IL-25. Brodalumab has been approved for the treatment of psoriasis vulgaris, psoriatic arthritis, pustular psoriasis and psoriatic erythroderma..

规格	价格	库存
1 mg	￥3580	In stock
5 mg	￥7580	In stock
10 mg	￥12800	In stock
100 mg		Get quote

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生物&药学活性

物理化学性质&存储条件

分子量
分子式	Human IgG2-Kappa
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	PBS, pH 7.0 Contains no stabilizers or preservatives
Chemical Name/SMILES	Brodalumab; Siliq; AMG-827; KHK-4827; Kyntheum; LP 0160; LUMICEF; 1174395-19-7; anti- human Interleukin 17A

参考文献

1. 1, Papp KA, et al. N Engl J Med. 2012 Mar 29;366(13):1181-9. 2, Spuls PI, et al. Br J Dermatol. 2012 Oct;167(4):710-3; discussion 714-5. 3, Martin DA, et al. Arthritis Res Ther. 2013 Oct 25;15(5):R164. 4, Kellner H. Ther Adv Musculoskelet Dis. 2013 Jun;5(3):141-52.

Brodalumab (Anti-human IL-17 mAb, human IgG2-Kappa; AMG-827; KHK-4827)

生物&药学活性

物理化学性质&存储条件

参考文献

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Brodalumab (Anti-human IL-17 mAb, human IgG2-Kappa; AMG-827; KHK-4827)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

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