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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-TRP Channel-Br-cis-22a
Br-cis-22a

Chemical Structure : Br-cis-22a

CAS No.:

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Br-cis-22a

货号: PC-25400Not For Human Use, Lab Use Only.

Br-cis-22a is a brominated PCHPD analog of TRPV6 inhibitor cis-22a, inhibits uptake of Cd2+ into hTRPV6-expressing HEK 293 cells with IC50 of 0.96 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Br-cis-22a is a brominated PCHPD analog of TRPV6 inhibitor cis-22a, inhibits uptake of Cd2+ into hTRPV6-expressing HEK 293 cells with IC50 of 0.96 uM.

物理化学性质&存储条件

分子量 414.39
分子式 C22H28BrN3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1-(5-bromopyridin-3-yl)-4-((1s,4s)-4-(m-tolyl)cyclohexyl)piperazine

参考文献

1. Bhardwaj R, et al. Sci Adv. 2020 Nov 27;6(48):eabe1508.

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