BpV(phen)

Chemical Structure : BpV(phen)

CAS No.: 42494-73-5

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货号: PC-23945Not For Human Use, Lab Use Only.

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50 mg	￥2180	In stock
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生物&药学活性

Bisperoxovanadium (bpV(phen)) is a bisperoxovanadium (bpV) compound which inhibits several different protein tyrosine phosphatases (PTPs), with selectivity for PTEN (IC50 =38 nM), also inhibits the vascular endothelial PTP, PTP-β (IC50=343 nM), and PTP-1β (IC50=920 nM).
Bisperoxovanadium activates the insulin receptor tyrosine kinase and promotes downstream signaling, including activation of PI3-kinase.

物理化学性质&存储条件

分子量	350.24
分子式	C12H8N2O5V.K
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	Vanadate(1-), oxodiperoxy(1,10-phenanthroline-κN1,κN10)-, potassium (1:1), (PB-7-23-111′1′3)-

参考文献

1. Chen Q, et al. J Biol Chem. 2015 Oct 23;290(43):26051-8.

2. Band CJ, et al. Mol Endocrinol. 1997 Dec;11(13):1899-910

BpV(phen)

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