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首页-小分子抑制剂&激动剂-GPCR-Melanocortin Receptor-Bivamelagon
Bivamelagon

Chemical Structure : Bivamelagon

CAS No.: 2641595-54-0

Bivamelagon (LB54640, LB-54640)

货号: PC-26948Not For Human Use, Lab Use Only.

Bivamelagon (LB54640) is a potent, selective, next-generation oral melanocortin receptor 4 (MC4R) agonist with EC50 of 0.562 nM (Luci assay) and 36.5 nM (cAMP assay).

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Bivamelagon (LB54640) is a potent, selective, next-generation oral melanocortin receptor 4 (MC4R) agonist with EC50 of 0.562 nM (Luci assay) and 36.5 nM (cAMP assay).

物理化学性质&存储条件

分子量 629.28
分子式 C35H53ClN4O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-((3S,5S)-1-((3S,4R)-1-(tert-butyl)-4-(4-chlorophenyl)pyrrolidine-3-carbonyl)-5-(morpholine-4-carbonyl)pyrrolidin-3-yl)-N-((1s,4R)-4-methylcyclohexyl)isobutyramide

参考文献

1. Patent WO2021091283 A1.

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