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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Glycine Transporter (GlyT)-Bitopertin R enantiomer
Bitopertin R enantiomer

Chemical Structure : Bitopertin R enantiomer

CAS No.: 845614-12-2

Bitopertin R enantiomer (RG-1678 R enantiomer, RO4917838 R enantiomer)

货号: PC-42707Not For Human Use, Lab Use Only.

Bitopertin R enantiomer is the R-enantiomer of Bitopertin, which is a potent and selective GlyT1 inhibitor with EC50 of 54 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    Bitopertin R enantiomer is the R-enantiomer of Bitopertin, which is a potent and selective GlyT1 inhibitor with EC50 of 54 nM.

    物理化学性质&存储条件

    分子量 543.455
    分子式 C21H20F7N3O4S
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    Methanone, [4-[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]-1-piperazinyl][5-(methylsulfonyl)-2-[(1R)-2,2,2-trifluoro-1-methylethoxy]phenyl]-

    参考文献

    1. Pinard E, et al. J Med Chem. 2010 Jun 24;53(12):4603-14.

    2. Alberati D, et al. Neuropharmacology. 2012 Feb;62(2):1152-61

    3. Martin-Facklam M, et al. Neuropsychopharmacology. 2013 Feb;38(3):504-12.

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