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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Acetylcholinesterase (AChE)-Bisnorcymserine
Bisnorcymserine

Chemical Structure : Bisnorcymserine

CAS No.: 219920-81-7

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Bisnorcymserine ((-)-Bisnorcymserine)

货号: PC-26807Not For Human Use, Lab Use Only.

Bisnorcymserine ((-)-Bisnorcymserine) is a potent inhibitor for butyrylcholinesterase (BChE) with IC50 of 0.228 nM, reduces the levels of amyloid-β peptide (Aβ), exhibits ameliorates AD in elderly rat models.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Bisnorcymserine ((-)-Bisnorcymserine) is a potent inhibitor for butyrylcholinesterase (BChE) with IC50 of 0.228 nM, reduces the levels of amyloid-β peptide (Aβ), exhibits ameliorates AD in elderly rat models.

物理化学性质&存储条件

分子量 351.45
分子式 C21H25N3O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(3aS,8aR)-3a-Methyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl (4-isopropylphenyl)carbamate

参考文献

1. Kamal MA, et al. J Alzheimers Dis. 2006 Sep;10(1):43-51.

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