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首页-小分子抑制剂&激动剂-GPCR-Dopamine Receptor-Benperidol
Benperidol

Chemical Structure : Benperidol

CAS No.: 2062-84-2

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Benperidol

货号: PC-27962Not For Human Use, Lab Use Only.

Benperidol is a potent butyrophenone antipsychotic with high affinity for the D2 dopamine receptor with Ki of 1-2 nM, selective over other dopamine and serotonin receptor subtypes, an antagonist of dopamine D2 receptor (D2R).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Benperidol is a potent butyrophenone antipsychotic with high affinity for the D2 dopamine receptor with Ki of 1-2 nM, selective over other dopamine and serotonin receptor subtypes, an antagonist of dopamine D2 receptor (D2R).

物理化学性质&存储条件

分子量 381.45
分子式 C22H24FN3O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

3-[1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl]-1H-benzimidazol-2-one

参考文献

1. Creese I, et al. Eur J Pharmacol. 1976 Mar;36(1):231-5.

2. Eisenstein SA, et al. J Psychiatr Res. 2017 Mar;86:9-17.

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