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首页-抗体和重组蛋白-Biosimilar Antibody-Belantamab
Belantamab

Chemical Structure : Belantamab

CAS No.: 2061894-48-0

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Belantamab (Anti-human BCMA mAb, human IgG1-Kappa)

货号: PC-Ab1042Not For Human Use, Lab Use Only.

B-cell maturation antigen (BCMA) is a cell-surface receptor of the tumour necrosis superfamily required for plasma cell survival. BMCA is universally detected on patient-derived myeloma cells and has emerged as a selective antigen to be targeted by novel treatments in multiple myeloma. Belantamab mafodotin (belamaf.

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1 mg ￥3580 In stock
5 mg ￥7580 In stock
10 mg ￥12800 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

B-cell maturation antigen (BCMA) is a cell-surface receptor of the tumour necrosis superfamily required for plasma cell survival. BMCA is universally detected on patient-derived myeloma cells and has emerged as a selective antigen to be targeted by novel treatments in multiple myeloma. Belantamab mafodotin (belamaf; BLENREP, GSK2857916) is a first-in-class antibody–drug conjugate (ADC) that targets B-cell maturation antigen (BCMA).

物理化学性质&存储条件

分子量
分子式 Human IgG1-Kappa
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

PBS, pH 7.0 Contains no stabilizers or preservatives
Chemical Name/SMILES

Belantamab; Belantamab mafodotin; 2061894-48-0;TNFRSF17; CD269; B-cell maturation antigen (BCMA); TNF Receptor Superfamily Member 17.

参考文献

1. 1, Tzogani K, et al. Oncologist. 2021 Jan;26(1):70-76. 2, Richardson PG, et al. Blood Cancer J. 2020 Oct 23;10(10):106. 3, Trudel S, et al. Lancet Oncol. 2018 Dec;19(12):1641-1653. 4, Lonial S, et al. Lancet Oncol. 2020 Feb;21(2):207-221.

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