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首页-抗体和重组蛋白-Biosimilar Antibody-Batoclimab
Batoclimab

Chemical Structure : Batoclimab

CAS No.: 2187430-05-1

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Batoclimab (Anti-human FcRn mAb, human IgG1-Lambda2; HBM9161; IMVT1401)

货号: PC-Ab1090Not For Human Use, Lab Use Only.

Batoclimab (HBM9161, IMVT1401) is a fully human IgG1 anti-FcRn mAb, blocks FcRn-IgG interactions, accelerating the degradation of autoantibodies and leads to the treatment of pathogenic IgG-mediated autoimmune diseases. The neonatal Fc receptor (also FcRn, IgG receptor FcRn large subunit p51, or Brambell receptor) is a protein that in humans is encoded by the FCGRT gene. It is an Fc receptor which is similar in structure to the MHC class I moleculethat functions to protect IgG and albumin from c

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1 mg ￥3580 In stock
5 mg ￥7580 In stock
10 mg ￥12800 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Batoclimab (HBM9161, IMVT1401) is a fully human IgG1 anti-FcRn mAb, blocks FcRn-IgG interactions, accelerating the degradation of autoantibodies and leads to the treatment of pathogenic IgG-mediated autoimmune diseases. The neonatal Fc receptor (also FcRn, IgG receptor FcRn large subunit p51, or Brambell receptor) is a protein that in humans is encoded by the FCGRT gene. It is an Fc receptor which is similar in structure to the MHC class I moleculethat functions to protect IgG and albumin from catabolism, mediates transport of IgG across epithelial cells, and is involved in antigen presentation by professional antigen presenting cells.

物理化学性质&存储条件

分子量
分子式 Human IgG1-Lambda2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

PBS, pH 7.0 Contains no stabilizers or preservatives
Chemical Name/SMILES

Batoclimab; HBM9161; HBM 9161; IMVT1401; IMVT-1401; HL 161; Anti-human neonatal Fc receptor for IgG; Anti-human FcRn; Fcgrt gene; Anti-human Brambell receptor; IgG receptor FcRn large subunit p51

参考文献

1. 1, Desmond Y H Yap, et al. Clin Transl Sci. 2021 Sep;14(5):1769-1779.

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