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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Influenza Virus-Baloxavir
Baloxavir

Chemical Structure : Baloxavir

CAS No.: 1985605-59-1

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Baloxavir (S-033447, Baloxavir acid, S033447)

货号: PC-35417Not For Human Use, Lab Use Only.

Baloxavir (S-033447, Baloxavir acid) is an anti-influenza compound that potently and selectively inhibits the cap-dependent endonuclease within the polymerase PA subunit of influenza A and B viruses.

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10 mg ￥2480 In stock
25 mg ￥3980 In stock
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纯度 & COA & 质检文件 纯度: 98.16% (HPLC) Select Batch:

生物&药学活性

Baloxavir (S-033447, Baloxavir acid) is an anti-influenza compound that potently and selectively inhibits the cap-dependent endonuclease within the polymerase PA subunit of influenza A and B viruses.
Baloxavir inhibits rgA/WSN/33 (H1N1) strain with EC50 of 0.42 nM.

物理化学性质&存储条件

分子量 483.49
分子式 C24H19F2N3O4S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(R)-12-((S)-7,8-difluoro-6,11-dihydrodibenzo[b,e]thiepin-11-yl)-7-hydroxy-3,4,12,12a-tetrahydro-1H-[1,4]oxazino[3,4-c]pyrido[2,1-f][1,2,4]triazine-6,8-dione

参考文献

1. Omoto S, et al. Sci Rep. 2018 Jun 25;8(1):9633.

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