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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Xanthine Oxidase (XAO)-Baicalein
Baicalein

Chemical Structure : Baicalein

CAS No.: 491-67-8

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Baicalein (5,6,7-Trihydroxyflavone)

货号: PC-24501Not For Human Use, Lab Use Only.

Baicalein (5,6,7-Trihydroxyflavone) is a xanthine oxidase (XO, xanthine oxidoreductase) inhibitor with IC50 of 3.12 uM, also is a noncovalent, nonpeptidomimetic inhibitor of SARS-CoV-2 3CLpro with potent antiviral activities, prevents cancer progression by inducing apoptosis, autophagy and genome instability.

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100 mg ￥580 In stock
250 mg ￥980 In stock
1 g ￥1380 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Baicalein (5,6,7-Trihydroxyflavone) is a xanthine oxidase (XO, xanthine oxidoreductase) inhibitor with IC50 of 3.12 uM, also is a noncovalent, nonpeptidomimetic inhibitor of SARS-CoV-2 3CLpro with potent antiviral activities, prevents cancer progression by inducing apoptosis, autophagy and genome instability.

物理化学性质&存储条件

分子量 270.24
分子式 C15H10O5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

5,6,7-Trihydroxyflavone

参考文献

1. Shieh DE,et al. Anticancer Res. 2000 Sep-Oct;20(5A):2861-5.

2. Song J, et al. Biochem Pharmacol. 2021 Jan;183:114302.

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