Bafilomycin D | V-ATPase inhibitor, SARS-CoV-2 inhibitor

Chemical Structure : Bafilomycin D

CAS No.: 98813-13-9

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Bafilomycin D (BafD)

货号: PC-24603Not For Human Use, Lab Use Only.

Bafilomycin D (BafD) is a specific V-ATPase inhibitor and potent nanomolar inhibitor of SARS-CoV-2 Omicron subvariants BA.5 and BA.2.

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500 mg	￥4980	In stock
1 mg	￥7980	In stock
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生物&药学活性

Bafilomycin D (BafD) is a specific V-ATPase inhibitor and potent nanomolar inhibitor of SARS-CoV-2 Omicron subvariants BA.5 and BA.2.
Bafilomycin D (BafD) exibibits a synergistic action with N-0385 (a highly potent inhibitor of human TMPRSS2 protease) against Omicron subvariant BA.2 in human Calu-3 lung cells.

物理化学性质&存储条件

分子量	604.83
分子式	C35H56O8
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	Oxacyclohexadeca-3,5,11,13-tetraen-2-one, 16-[(1S,2R,3S,5E,7S,8R)-2,8-dihydroxy-1,3,7,9-tetramethyl-4-oxo-5-decen-1-yl]-8-hydroxy-3,15-dimethoxy-5,7,9,11-tetramethyl-, (3Z,5E,7R,8S,9S,11E,13E,15S,16R)-

参考文献

1. Pérez-Vargas J, et al. Antiviral Res. 2023 Jan;209:105484.

2. Tchize Ndejouong Ble S, et al. J Antibiot (Tokyo). 2010 Jul;63(7):359-63.

3. Pérez-Vargas J, et al. Emerg Microbes Infect. 2023 Dec;12(2):2246594.

Bafilomycin D (BafD)

生物&药学活性

物理化学性质&存储条件

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Bafilomycin D (BafD)

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