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首页-小分子抑制剂&激动剂-Proteasome/Ubiquitin-Heat Shock Protein (HSP)-BX-2819
BX-2819

Chemical Structure : BX-2819

CAS No.: 1184181-50-7

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BX-2819 (BX2819)

货号: PC-21297Not For Human Use, Lab Use Only.

BX-2819 is a potent, selective Hsp90 inhibitor with KD of 16.4 nM for human Hsp90α, also is a potent B. burgdorferi high-temperature protein G (Bb HtpG) with KD of 12 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    BX-2819 is a potent, selective Hsp90 inhibitor with KD of 16.4 nM for human Hsp90α, also is a potent B. burgdorferi high-temperature protein G (Bb HtpG) with KD of 12 nM.

    物理化学性质&存储条件

    分子量 428.51
    分子式 C21H24N4O4S
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    ethyl (4-(3-(2,4-dihydroxy-5-isopropylphenyl)-5-thioxo-1,5-dihydro-4H-1,2,4-triazol-4-yl)benzyl)carbamate

    参考文献

    1. Dave L Carlson, et al. Cell Chem Biol. 2023 Oct 26:S2451-9456(23)00340-9.

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