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BTKi-2

Chemical Structure : BTKi-2

CAS No.: 1558036-85-3

BTKi-2 (BTK inhibitor-2, Btk inhibitor 2)

货号: PC-27129Not For Human Use, Lab Use Only.

BTKi-2 (Btk inhibitor 2) is a highly potent BTK inhibitor with IC50 of 0.18 nM, also exhibits IC50 of 535 nM against vaccinia virus (VACV) and 260 nM against MPXV in vitro.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

BTKi-2 (Btk inhibitor 2) is a highly potent BTK inhibitor with IC50 of 0.18 nM, also exhibits IC50 of 535 nM against vaccinia virus (VACV) and 260 nM against MPXV in vitro.

物理化学性质&存储条件

分子量 431.50
分子式 C24H25N5O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-1-(1-acryloylpiperidin-3-yl)-5-amino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carboxamide

参考文献

1. Mark E Schnute, et al. ACS Med Chem Lett. 2018 Dec 3;10(1):80-85.

2. Chen Yang, et al. Virol Sin. 2026 Jun 19:S1995-820X(26)00100-8.

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