Chemical Structure : BSJ-03-204
CAS No.: 2349356-09-6
货号: PC-73288Not For Human Use, Lab Use Only.
BSJ-03-204 is a dual and selective degrader (PROTAC) of CDK4 and CDK6 with IC50 of 26.9 nM and 10.4 nM for CDK4/D1 and CDK6/D1, respectively, does not induce IKZF1/3 degradation.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 mg | ¥2480 | In stock | |
| 10 mg | ¥3880 | In stock | |
| 25 mg | ¥5980 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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BSJ-03-204 is a dual and selective degrader (PROTAC) of CDK4 and CDK6 with IC50 of 26.9 nM and 10.4 nM for CDK4/D1 and CDK6/D1, respectively, does not induce IKZF1/3 degradation.
| 分子量 | 832.91 | |
| 分子式 | C43H48N10O8 | |
| 外观性状 | Solid | |
| 储存条件 |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
N-(4-(4-(6-((6-Acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazin-1-yl)butyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide |
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1. Baishan Jiang, et al. Angew Chem Int Ed Engl. 2019 May 6;58(19):6321-6326.
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