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BSH-IN-1

Chemical Structure : BSH-IN-1

CAS No.: 2553217-91-5

BSH-IN-1

货号: PC-27804Not For Human Use, Lab Use Only.

BSH-IN-1 is a potent and covalent inhibitor of gut bacterial bile salt hydrolases (BSHs) with IC50s of 108 nM and 427 nM for B. longum BSH (Gram positive) and B. theta BSH (Gram negative), respectively.

规格 价格 库存 数量
25 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

BSH-IN-1 is a potent and covalent inhibitor of gut bacterial bile salt hydrolases (BSHs) with IC50s of 108 nM and 427 nM for B. longum BSH (Gram positive) and B. theta BSH (Gram negative), respectively.

物理化学性质&存储条件

分子量 408.60
分子式 C25H41FO3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-5-((3R,5S,7R,8R,9S,10S,13R,14S,17R)-3,7-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-1-fluorohexan-2-one

参考文献

1. Arijit A Adhikari, et al. Nat Chem Biol. 2020 Mar;16(3):318-326.

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