BRD 8430 |CAS:1482499-16-0 Probechem Biochemicals

Chemical Structure : BRD 8430

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BRD 8430 (BRD8430)

货号: PC-62467Not For Human Use, Lab Use Only.

BRD 8430 is a potent, selective class I HDAC inhibitor (HDAC1>2 >3) with IC50 of 69 nM/560/1300 nM for HDAC1/2/3, respectively.

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生物&药学活性

BRD 8430 is a potent, selective class I HDAC inhibitor (HDAC1>2 >3) with IC50 of 69 nM/560/1300 nM for HDAC1/2/3, respectively.
BRD 8430 shows no activity against other HDACs.
BRD 8430 decreases viability and induces differentiation of neuroblastoma cell lines.

物理化学性质&存储条件

分子量	573.738
分子式	C33H43N5O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(2-aminophenyl)-4-[[[(2R,3S)-9-(dimethylamino)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-2,3,4,7-tetrahydro-1,5-benzoxazonin-2-yl]methyl-methylamino]methyl]benzamide

参考文献

1. Frumm SM, et al. Chem Biol. 2013 May 23;20(5):713-25.

BRD 8430 (BRD8430)

生物&药学活性

物理化学性质&存储条件

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BRD 8430 (BRD8430)

生物&药学活性

物理化学性质&存储条件

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