BMX inhibitor 11i | BMX inhibitor | Probechem Biochemicals

Chemical Structure : BMX inhibitor 11i

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BMX inhibitor 11i (BMX-IN-2)

货号: PC-27275Not For Human Use, Lab Use Only.

BMX inhibitor 11i (BMX-IN-2) is a potent, selective TEC family member BMX kinase with IC50 of 1.78 nM and EC50 of 98 nM in NanoBRET assays, 20-fold selective over BTK.

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生物&药学活性

BMX inhibitor 11i (BMX-IN-2) is a potent, selective TEC family member BMX kinase with IC50 of 1.78 nM and EC50 of 98 nM in NanoBRET assays, 20-fold selective over BTK.

物理化学性质&存储条件

分子量	422.89
分子式	C21H15ClN4O2S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(3-(3-Acrylamidophenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl)-5-chlorothiophene-2-carboxamide

参考文献

1. Liang XJ, et al. J Med Chem. 2026 Jul 13. doi: 10.1021/acs.jmedchem.6c01366.

BMX inhibitor 11i (BMX-IN-2)

生物&药学活性

物理化学性质&存储条件

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BMX inhibitor 11i (BMX-IN-2)

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物理化学性质&存储条件

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