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首页-小分子抑制剂&激动剂-GPCR-Opioid Receptor-BMS-986122
BMS-986122

Chemical Structure : BMS-986122

CAS No.: 313669-88-4

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BMS-986122 (BMS986122)

货号: PC-22780Not For Human Use, Lab Use Only.

BMS-986122 is a positive allosteric modulator of μ-opioid receptor (MOR) with EC50 of 3.0 uM for increased β-arrestin recruitment by 20 nM endomorphin-I.

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10 mg ￥1480 In stock
25 mg ￥2580 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

BMS-986122 is a positive allosteric modulator of μ-opioid receptor (MOR) with EC50 of 3.0 uM for increased β-arrestin recruitment by 20 nM endomorphin-I.

物理化学性质&存储条件

分子量 448.77
分子式 C16H15BrClNO3S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-(3-Bromo-4-methoxyphenyl)-3-[(4-chlorophenyl)sulfonyl]thiazolidine

参考文献

1. Burford NT, et al. Proc Natl Acad Sci U S A. 2013 Jun 25;110(26):10830-5.

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