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首页-小分子抑制剂&激动剂-Others-Other Targets-BMS-354326
BMS-354326

Chemical Structure : BMS-354326

CAS No.: 708258-16-6

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BMS-354326 (BMS354326)

货号: PC-25176Not For Human Use, Lab Use Only.

BMS-354326 is a highly potent, selective tryptase inhibitor with IC50 of 1.8 nM, shows excellent selectivity against trypsin and most other related serine proteases.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

BMS-354326 is a highly potent, selective tryptase inhibitor with IC50 of 1.8 nM, shows excellent selectivity against trypsin and most other related serine proteases.
BMS-354326 is over 5000-fold selective against trypsin. 

物理化学性质&存储条件

分子量 512.65
分子式 C28H40N4O5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(2S,3R)-4-oxo-1-(4-(6-phenylhexanoyl)piperazine-1-carbonyl)-3-(2-(piperidin-3-yl)ethyl)azetidine-2-carboxylic acid

参考文献

1. Bisacchi GS, et al. Bioorg Med Chem Lett. 2004 May 3;14(9):2227-31.

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