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首页-小分子抑制剂&激动剂-Immunology/Inflammation-PD-1/PD-L1-BMS-1
BMS-1

Chemical Structure : BMS-1

CAS No.: 1675201-83-8

BMS-1 (PD-1/PD-L1 inhibitor 1)

货号: PC-45776Not For Human Use, Lab Use Only.

BMS-1 (PD1/PD-L1 inhibitor 1) is a potent PD-1/PD-L1 interaction inhibitor with IC50 of 6-100 nM in a homogenous time-resolved fluorescence binding assay.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

BMS-1 (PD1/PD-L1 inhibitor 1) is a potent PD-1/PD-L1 interaction inhibitor with IC50 of 6-100 nM in a homogenous time-resolved fluorescence binding assay.

物理化学性质&存储条件

分子量 475.576
分子式 C29H33NO5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 29 mg/mL

Chemical Name/SMILES

2-Piperidinecarboxylic acid, 1-[[2,6-dimethoxy-4-[(2-methyl[1,1'-biphenyl]-3-yl)methoxy]phenyl]methyl]-, (2S)-

参考文献

1. Chupak, L.S., and Zheng, X. Compounds useful as immunomodulators. PCT/US2014/053695, (2015).

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