BIM1

首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Chloride Channel-BIM1

Chemical Structure : BIM1

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货号: PC-27985Not For Human Use, Lab Use Only.

BIM1 is a specific small molecule inhibitor of chloride channel CLC-Ka (CLCNKA) with IC50 of 8.5 uM, >20-fold selectivity for CLC-Ka over CLC-Kb.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

BIM1 is a specific small molecule inhibitor of chloride channel CLC-Ka (CLCNKA) with IC50 of 8.5 uM, >20-fold selectivity for CLC-Ka over CLC-Kb.

物理化学性质&存储条件

分子量	381.27
分子式	C13H7Cl2KN2O3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	potassium 6-chloro-1-(2-chlorophenyl)-1H-benzo[d]imidazole-2-sulfonate

参考文献

1. Koster AK, et al. Proc Natl Acad Sci U S A. 2018 May 22;115(21):E4900-E4909.

2. Chien CT, et al. Proc Natl Acad Sci U S A. 2026 Sep 8;123(36):e2605886123.

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BIM1

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BIM1

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