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首页-小分子抑制剂&激动剂-Others-Other Targets-BI 1595043
BI 1595043

Chemical Structure : BI 1595043

CAS No.: 2412577-05-8

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BI 1595043 (BI-1595043)

货号: PC-25561Not For Human Use, Lab Use Only.

BI 1595043 is a potent, selective and orally bioavailable Vanin (vanin‐1 and vanin‐2) inhibitor, demonstrates promising effects on epithelial cell protection and reduction of inflammatory mediators in preclinical studies.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

BI 1595043 is a potent, selective and orally bioavailable Vanin (vanin‐1 and vanin‐2) inhibitor, demonstrates promising effects on epithelial cell protection and reduction of inflammatory mediators in preclinical studies.

物理化学性质&存储条件

分子量 396.47
分子式 C22H25FN4O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-[(3S)-1-[(2R)-2-(4-fluorophenyl)-2-methyl-1H,2H,3H-pyrrolo[2,3-b]pyridine-5-carbonyl]pyrrolidin-3-yl]-N-methylacetamide

参考文献

1. Anjli Kukreja, et al. Clin Transl Sci. 2025 Sep;18(9):e70285.

2. Patent WO2020043658 A1.

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