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首页-小分子抑制剂&激动剂-Others-PHGDH-BI-4924
BI-4924

Chemical Structure : BI-4924

CAS No.: 2244452-09-1

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BI-4924 (BI 4924)

货号: PC-72878Not For Human Use, Lab Use Only.

BI-4924 (BI 4924) is a potent, selective NADH/NAD+-competitive PHGDH inhibitor with IC50 of 2 nM.

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2 mg ￥2580 In stock
5 mg ￥4580 In stock
10 mg ￥7580 In stock
50 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

BI-4924 (BI 4924) is a potent, selective NADH/NAD+-competitive PHGDH inhibitor with IC50 of 2 nM.
BI-4924 displays high selectivity against the majority of other dehydrogenase targets.

物理化学性质&存储条件

分子量 499.359
分子式 C21H20Cl2N2O6S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-{4-[(1S)-1-[(4,5-Dichloro-1,6-dimethyl-1H-indol-2-yl)formamido]-2-hydroxyethyl]benzenesulfonyl}acetic acid

参考文献

1. Harald Weinstabl, et al. J Med Chem. 2019 Sep 12;62(17):7976-7997.

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