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首页-小分子抑制剂&激动剂-Others-Other Targets-BCT2029
BCT2029

Chemical Structure : BCT2029

CAS No.: 3079354-66-5

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BCT2029 (BCT-2029)

货号: PC-27395Not For Human Use, Lab Use Only.

BCT2029 is a potent Biliverdin IXb reductase (BLVRB, biliverdin reductase IXβ) inhibitor, inhibits BLVRB reductive activity using both FMN (flavin mononucleotide, IC50=194 nM) and DCPIP (2,6-dichlorophenolindophenol; IC50=28 nM) as substrates.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

BCT2029 is a potent Biliverdin IXb reductase (BLVRB, biliverdin reductase IXβ) inhibitor, inhibits BLVRB reductive activity using both FMN (flavin mononucleotide, IC50=194 nM) and DCPIP (2,6-dichlorophenolindophenol; IC50=28 nM) as substrates.

物理化学性质&存储条件

分子量 359.39
分子式 C21H17N3O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

3-(3-ethyl-7-oxo-2-phenyl-1,7-dihydropyrazolo[1,5-a]pyrimidin-5-yl)benzoic acid

参考文献

1. Rahul Raghavan Thekke Veedu, et al. J Med Chem. 2026 Jul 27. doi: 10.1021/acs.jmedchem.6c01466.

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