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BC8a

Chemical Structure : BC8a

CAS No.: 2363753-48-2

BC8a (ClpP inhibitor 8a)

货号: PC-25347Not For Human Use, Lab Use Only.

BC8a (ClpP inhibitor 8a) is a potent inhibitor of hClpP with IC50 of 10.2 uM, inhibits hClpP peptidase activity, also inhibits the holoenzyme hClpXP.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

BC8a (ClpP inhibitor 8a) is a potent inhibitor of hClpP with IC50 of 10.2 uM, inhibits hClpP peptidase activity, also inhibits the holoenzyme hClpXP.

物理化学性质&存储条件

分子量 412.72
分子式 C19H30BClN2O5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

((R)-1-((S)-2-(2-Chloro-4-methoxybenzamido)-4-methylpentanamido)-3-methylbutyl)boronic Acid

参考文献

1. Tan J, et al. J Med Chem. 2019 Jul 11;62(13):6377-6390.

2. Barghash MM, et al. Structure. 2025 Aug 5:S0969-2126(25)00261-8.

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