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首页-小分子抑制剂&激动剂-Others-Other Targets-BC-DXI-843
BC-DXI-843

Chemical Structure : BC-DXI-843

CAS No.: 2421117-98-6

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BC-DXI-843

货号: PC-23516Not For Human Use, Lab Use Only.

BC-DXI-843 is a potent and specific AIMP2-DX2 inhibitor with IC50 og 0.92 uM, >100-fold selectivity over AIMP2.

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5 mg ￥980 In stock
10 mg ￥1480 In stock
25 mg ￥2580 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

BC-DXI-843 is a potent and specific AIMP2-DX2 inhibitor with IC50 og 0.92 uM, >100-fold selectivity over AIMP2.
BC-DXI-843 suppresses cancer cell proliferation in a DX2-dependent manner with EC50 of 1.2 uM in A549 cells.

物理化学性质&存储条件

分子量 546.66
分子式 C28H26N4O4S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(S)-3-(1H-Indol-3-yl)-N-(4-(4-methoxyphenyl)thiazol-2-yl)-2-(4-methylphenylsulfonamido)propanamide

参考文献

1. Aneesh Sivaraman, et al. J Med Chem. 2020 May 28;63(10):5139-5158.

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