欢迎访问ProbeChem中文网站，英文网站请访问www.probechem.com
    英文 |     中文

产品咨询: sales@probechem.com
订购: order@probechem.com

首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-Checkpoint Kinase (Chk)-BBI-355
BBI-355

Chemical Structure : BBI-355

CAS No.: 3017958-71-0

加入收藏

BBI-355 (BBI 355, BBI355)

货号: PC-27305Not For Human Use, Lab Use Only.

BBI-355 is a potent, selective, and orally available Checkpoint kinase 1 (CHK1) inhibitor with IC50 of 0.6 nM, shows >150-fold selectivity over CHK2, demonstrates strong antitumor activity.

规格 价格 库存 数量
25 mg Get quote
50 mg Get quote
100 mg Get quote
获取报价单
* 请选择数量再加入购物车
 or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

BBI-355 is a potent, selective, and orally available Checkpoint kinase 1 (CHK1) inhibitor with IC50 of 0.6 nM, shows >150-fold selectivity over CHK2, demonstrates strong antitumor activity.

物理化学性质&存储条件

分子量 406.45
分子式 C20H22N8O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

5-((5-(4-(((1R,3S)-3-aminocyclopentyl)oxy)-2-methoxy-6-methylpyridin-3-yl)-1H-pyrazol-3-yl)amino)pyrazine-2-carbonitrile

参考文献

1. Meyer ST, et al. J Med Chem. 2026 Jul 15. doi: 10.1021/acs.jmedchem.6c00822.

备案号：沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

联系我们 sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

询单

  • *产品名称:
  • *姓名:
  • *邮箱:
  • *公司名称:
  • *询单数量:
  • *国籍:
  • 询单信息: