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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Bacterial-BB-78485
BB-78485

Chemical Structure : BB-78485

CAS No.: 207732-11-4

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BB-78485 (BB78485)

货号: PC-26544Not For Human Use, Lab Use Only.

BB-78485 is a potent inhibitor of LpxC with IC50 of 160 nM in E. coli LpxC assays, showspredominantly gram-negative activities with MIC of 2 ug/mL for E.coli D21.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

BB-78485 is a potent inhibitor of LpxC with IC50 of 160 nM in E. coli LpxC assays, showspredominantly gram-negative activities with MIC of 2 ug/mL for E.coli D21.

物理化学性质&存储条件

分子量 420.48
分子式 C23H20N2O4S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(R)-N-Hydroxy-3-(naphthalen-2-yl)-2-(naphthalene-2-sulfonamido)propanamide

参考文献

1. Clements JM,et al. Antimicrob Agents Chemother. 2002 Jun;46(6):1793-9.

2. Mochalkin I, et al. Protein Sci. 2008 Mar;17(3):450-7.

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