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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Phospholipase-BAY-439
BAY-439

Chemical Structure : BAY-439

CAS No.:

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BAY-439 (BAY439)

货号: PC-26792Not For Human Use, Lab Use Only.

BAY-439 is a potent and selective inhibitor of human phospholipase A2 Group V (hPLA2-G5) with biochemical IC50 of 7 nM and KD of 214 nM in the SPR binding assay.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

BAY-439 is a potent and selective inhibitor of human phospholipase A2 Group V (hPLA2-G5) with biochemical IC50 of 7 nM and KD of 214 nM in the SPR binding assay.

物理化学性质&存储条件

分子量 364.45
分子式 C21H24N4O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4-(4-((2-(ethylamino)pyridin-4-yl)ethynyl)phenoxy)piperidine-1-carboxamide

参考文献

1. Langer G, et al. J Med Chem. 2026 May 19. doi: 10.1021/acs.jmedchem.6c00488.

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